Traumatic brain injury (TBI) in adolescents and adults can result in cognitive, emotional, behavioral and neurological deficits that can persist more than a year after an injury. The current preliminary study used 3D magnetic resonance spectroscopic imaging (MRSI) and comprehensive neuropsychological assessment to determine if prolonged cerebral metabolic and cognitive alterations occur in individuals with persistent neurocognitive deficits following a mild TBI (mTBI). The current study evaluated the potential interactions between cerebral metabolism and neuropsychological performance, coping style, mood, and perceived quality of life in mTBI subjects with chronic post-concussive symptoms. The mTBI subjects performed worse than controls on neuropsychological measures, endorsed poorer mood and reported significantly poorer perceived quality of life than healthy controls. Additionally, cerebral metabolic differences were found between groups as well as significant interactions between neuropsychological performance and cerebral metabolism. The current findings may potentially guide future research to more eagerly strive to understand possible ways to alter cerebral metabolism, possibly through medication, diet, or other behavioural changes.
School of Behavioral Health
Ropacki, Susan A.
Vermeersch, David A.
Doctor of Philosophy (PhD)
Year Degree Awarded
Date (Title Page)
Library of Congress/MESH Subject Headings
Brain injuries; Trauma; Brain - metabolism;
Subject - Local
Mild Traumatic Brain Injury, Cerebral metabolism, Neuropsychological performance
Loma Linda University Libraries
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Evans, Julia L., "Cerebral Metabolic and Neuropsychological Outcomes Following Mild Traumatic Brain Injury" (2013). Loma Linda University Electronic Theses, Dissertations & Projects. Paper 120.
Loma Linda University Electronic Theses & Dissertations
Loma Linda University. Del E. Webb Memorial Library. University Archives