Abstract
The bactericidal test has been used to determine whether the consumption of concentrated carbohydrate affects the ability of human leukocytes to destroy bacteria. Subjects were given a dose of 100 grams of glucose. Two hours later a blood sample was drawn and incubated with Staphylococcus epidermidis for 120 minutes. There was no significant difference in the bactericidal activity of leukocytes of blood two hours following the ingestion of glucose from the bactericidal activity of fasting blood. A count done simultaneously with the bactericidal tests of the average number of single cocci engulfed per polymorphonuclear leukocyte showed a slightly lower phagocytic index in blood collected two hours after the ingestion of glucose than in fasting blood.
There is evidence to indicate that the ability of the neutrophil to phagocytize particles was impaired by post prandial blood glucose levels. However, once organisms had entered the neutrophil the ability of the cell to kill the organisms was not affected by blood glucose levels.
Department
Nutrition
School
Graduate School
First Advisor
Albert Sanchez
Second Advisor
Benjamin H. S. Lau
Third Advisor
Paul J. McMillan
Fourth Advisor
U. D. Register
Fifth Advisor
Rodney E. Willard
Sixth Advisor
Paul Y. Yahiku
Degree Name
Master of Science (MS)
Degree Level
M.S.
Year Degree Awarded
1974
Date (Title Page)
8-1974
Language
English
Library of Congress/MESH Subject Headings
Glucose; Neutrophils
Type
Thesis
Page Count
vi; 66
Digital Format
Digital Publisher
Loma Linda University Libraries
Copyright
Author
Usage Rights
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Recommended Citation
Corder, Carolyn Ann, "The Bactericidal Activity of Human Polymorphonuclear Leukocytes Before and After the Ingestion of Glucose" (1974). Loma Linda University Electronic Theses, Dissertations & Projects. 1363.
https://scholarsrepository.llu.edu/etd/1363
Collection
Loma Linda University Electronic Theses and Dissertations
Collection Website
http://scholarsrepository.llu.edu/etd/
Repository
Loma Linda University. Del E. Webb Memorial Library. University Archives