Abstract

The effect of a high unsaturated-low saturated fat diet on serum cholesterol levels were studied. Subjects were clinic patients receiving the following hypocholesterolmeic agents: triparanol (MER-29), diildothyroacetic acid (Diac), dextrothyroxine (d-T4) and 3-methoxy-16, alpha-methyl-1,3,5, (10)-estratriene-16 beta, 17 beta-diol (Manvene or Anvene).

Fifteen hypercholesterolemic patients, eleven of whom were diabetic, were placed on diets with prescribed amounts of unsaturated fat. The caloric distribution was 40 per cent carbohydrate, 20 per cent protein, and 40 per cent fat. The level of unsaturated fat was 70 per cent of the total fat.

Seventy-one per cent of the patients on the hypocholesterolemic agents had an overall decrease in serum cholesterol. There was an overall increase in serum cholesterol in 85.5 per cent of the patients not on drug therapy. There was no significant change observed in weight, serum glucose, or serum cholesterol.

Using serum cholesterol as the main criterion for evaluating the efficacy of the diet, the results of this study do not appear to be significant.

Department

Nutrition

School

Graduate Studies

First Advisor

Phyllis Acosta

Second Advisor

Ruth Little

Third Advisor

Burt Cochran

Fourth Advisor

U. D. Register

Fifth Advisor

Irma Vyhmeister

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1961

Date (Title Page)

6-1961

Language

English

Library of Congress/MESH Subject Headings

Fats; Unsaturated Cholesterol; Dietary; Anticholesteremic Agents

Type

Thesis

Page Count

vii; 59

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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