Sixteen healthy male subjects were randomly divided into four equal groups and fed a nutritionally balanced 30 calories % fat diet, with approximately 2500 calories and less than 15 mg cholesterol/day, for 28 days. Within each group a constant level of linoleic acid was given for the duration of the study--either 2, 6, 14 or 18 % linoleic acid. Rate of changes in total cholesterol, HDL cholesterol and the ratio of total to HDL-cholesterol were subjected to analysis of variance and regression analysis. The results showed changes in total cholesterol and ratio of total to HDL-cholesterol to be significant. The more unsaturated fat intakes (14% and 18%) decreased total cholesterol over time while the more saturated fat intakes (2% and 6%) increased total cholesterol. No definite trends in HDL-cholesterol were observed, though all groups increased slightly. Ratio of total to HDL-cholesterol decreased in all groups except the group with the lowest linoleic acid intake, which had an increase in ratio. At 30 calories % fat intake the results of this study suggest that optimum linoleic acid intake lies between 6 and 14%.
Master of Science (MS)
Year Degree Awarded
Date (Title Page)
Library of Congress/MESH Subject Headings
Dental Cements; Composite Resins; Pit and Fissure Sealants
Loma Linda University Libraries
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Davidge, Donna Miller, "The Effects of Varying Levels of Dietary Linoleic Acid on Serum Cholesterol and HDL-Cholesterol in Healthy Male Subjects" (1979). Loma Linda University Electronic Theses, Dissertations & Projects. 1675.
Loma Linda University Electronic Theses and Dissertations
Loma Linda University. Del E. Webb Memorial Library. University Archives