This investigation concerns the relationship of diabetes mellitus and vascular hypertension to oral lichen planus. Questionnaires were sent to 470 patients with oral lichen planus: 286 responded. Of these patients 103 were examined clinically, and 74 with current lesions were divided into ''keratotic'' and ''erosive'' categories. These patients underwent three-hour oral glucose tolerance tests; also, their asterial blood pressure was determined. In the survey group, diabetes was reported about three times more frequently by those with "erosive"; oral lichen planus than by those ''keratoic" lesions. The overall prevalence of diabetes was about two and one-half times greater than expected compared to its estimated rate in the general population. In the smaller clinical group that underwent oral glucose tolerance tests, diabetes was found about six times more frequently than expected but was less affected by the type of lichen planus. Hypertension was reported less frequently than expected in the survey group but was more prevalent than expected in the clinical group, with little difference in rate noted between lichen planus categories. The association of oral lichen planus and diabetes was confirmed, and was made more remarkable when new cases of diabetes and hypertension were discovered in the clinical group. The coexistence of hypertension was less pronounced. The simultaneous occurrence of the three diseases was more common in the clinical group but was not striking.
Francis V. Howell
Albert M. Abrams
Elmer E. Kelln
William P. Thompson
Master of Science (MS)
Year Degree Awarded
Date (Title Page)
Library of Congress/MESH Subject Headings
Lichen Planus; Hypertension; Diabetes Mellitus
Loma Linda University Libraries
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Rick, Gordon M., "Oral Lichen Planus : A Clinical Study of the Association with Diabetes Mellitus and Vascular Hypertension" (1972). Loma Linda University Electronic Theses, Dissertations & Projects. 2074.
Loma Linda University Electronic Theses and Dissertations
Loma Linda University. Del E. Webb Memorial Library. University Archives