Title

Serum phospholipid-cholesterol ratios in coronary atherosclerosis: II. Response to lipotropic agents

Document Type

Article

Publication Date

1-1-1953

Publication Title

Angiology

ISSN

00033197

E-ISSN

19401574

Abstract

1. A series of 28 patients with coronary thrombosis and infarction were tested by a 23 gm low fat-low cholesterol daily dietary together with combinations of lipotropic agents for 6 months. 2. The lipotropic combination consisted of 3 gm of choline, 2 gm of inositol, 4 gm of methionine and natural B complex obtained from 12 gm of liver, administered orally every day for 6 months. 3. Serum phospholipid/cholesterol ratios were determined before and after treatment with diet and lipotropic agents. 4. By reducing the exogenous dietary fat and cholesterol intake serum cholesterol levels were reduced. By increasing the exogenous source of phospholipids through the ingestion of adequate amounts of lipotropic substances, serum phospholipids were elevated. 5. In this series of 28 patients with coronary atherosclerosis subnormal serum/phospholipid/cholesterol ratios below 1.0 were restored to normal levels above 1.0 by the method of treatment described. © 1953, Sage Publications. All rights reserved.

Volume

4

Issue

2

First Page

130

Last Page

133

DOI

10.1177/000331975300400205

PubMed ID

13040818

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