Title

Alterations in cerebrospinal fluid protein following pantopaque myelography

Document Type

Article

Publication Date

1-1-1960

Publication Title

Experimental Neurology

ISSN

00144886

E-ISSN

10902430

Abstract

The injection of 0.5 or 1 ml of pantopaque (ethyl iodophenylundecylate) into the cistern of cats produced an elevation in cerebrospinal fluid protein. This elevation was usually observed within the first 2 postmyelographic weeks and persisted for approximately 4 months. The protein response was accompanied by a comparable elevation in the cerebrospinal fluid white cell level. Repeated cisternal punctures alone had no effect on consequent protein or cell determinations. The data suggest that intrathecal pantopaque elicits a meningovascular response of an inflammatory nature, although the clinical course of the animal remains asymptomatic. The probability that pantopaque elicits a similar response in man is discussed. © 1960.

Volume

2

Issue

1

First Page

62

Last Page

74

DOI

10.1016/0014-4886(60)90048-0

PubMed ID

13811196

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