Report Title

The Effect of Probiotic Supplementation on Gastrointestinal Quality of Life

Collective Title

Master of Science in Nutrition and Dietetics Research Reports 2017


Purpose. The purpose of this research study was to investigate the effect of Puritan’s Pride probiotic on gastrointestinal quality of life of working adults at the Loma Linda Support Services Building aged 18 to 65 years. Methods. Working adults, 18 to 65 years of age, from the Loma Linda Support Services Building were eligible to participate in the study. Subjects were excluded if they were taking antibiotics or had taken antibiotics within the previous six months. Subjects who consented were given an initial Gastrointestinal Quality of Life Index (GIQLI)12 test and a probiotic supplement for 60 days. Subjects’ body composition was also tested during the initial visit. After the 60 days of supplementation, subjects returned to retake the GIQLI and to retest their body composition. Results. Eleven subjects, 1 male and 10 females, reported for post intervention GIQLI and body composition testing. A mean increase of 10.7 (SD= 11.1) in GIQLI scores was found after probiotic supplementation (p = .009). No significant differences were found in pre and postintervention measurements for BMI, body fat, and weight. The best predictor of postintervention GIQLI scores was preintervention GIQLI scores. Conclusion. There was an improvement in the related gastrointestinal quality of life in our subjects as shown through a significant increase in GIQLI scores and subjects’ commentary. The best predictor of posttest GIQLI scores was pretest GIQLI scores.

LLU Discipline

Nutrition and Dietetics


Nutrition and Dietetics


School of Allied Health Professions

First Advisor

Schneider, Louise

Second Advisor

Noval, JeJe

Degree Name

Master of Science (MS)

Degree Level


Year Degree Awarded


Date (Title Page)




Library of Congress/MESH Subject Headings

Probiotics; Gastrointestinal System; Quality of Life


Probiotic; Supplementation; Microbiome; GIQLI; Digestion


Research Report

Page Count

15 p.

Digital Format


Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.


Loma Linda University Research Reports

Collection Website


Loma Linda University. University Libraries.