Abstract

Samples of blood were obtained from thirty healthy young adult males (Loma Linda University School of Dentistry), and contaminated with bacteria. Varying concentrations of pure glucose were added to this mixture to observe the effect of the glucose on in vitro neutrophilic phagocytosis. As the glucose levels increased a statistically significant suppression was noted in the ability of the neutrophilic leukocytes to engulf Staphylococcus epidermidis.

It was not possible, however, to predict the degree of suppression for any particular level of glucose added nor is it possible to state that suppression will occur in any one individual.

Two methods of phagocytic index determinations were used. The first recorded the percentage of neutrophils that had phagocytized and the second counted the number of bacteria per phagocyte. Statistically no difference was noted between the two methods.

LLU Discipline

Periodontics

Department

Periodontics

School

Graduate School

First Advisor

Edwin M. Collins

Second Advisor

Charles T. Smith

Third Advisor

Ralph R. Steinman

Fourth Advisor

Richard C. Oliver

Fifth Advisor

Alvin V. Schiess

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1967

Date (Title Page)

6-1967

Language

English

Library of Congress/MESH Subject Headings

Glucose; Phagocytosis

Type

Thesis

Page Count

vi; 50

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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