Abstract
Samples of blood were obtained from thirty healthy young adult males (Loma Linda University School of Dentistry), and contaminated with bacteria. Varying concentrations of pure glucose were added to this mixture to observe the effect of the glucose on in vitro neutrophilic phagocytosis. As the glucose levels increased a statistically significant suppression was noted in the ability of the neutrophilic leukocytes to engulf Staphylococcus epidermidis.
It was not possible, however, to predict the degree of suppression for any particular level of glucose added nor is it possible to state that suppression will occur in any one individual.
Two methods of phagocytic index determinations were used. The first recorded the percentage of neutrophils that had phagocytized and the second counted the number of bacteria per phagocyte. Statistically no difference was noted between the two methods.
LLU Discipline
Periodontics
Department
Periodontics
School
Graduate School
First Advisor
Edwin M. Collins
Second Advisor
Charles T. Smith
Third Advisor
Ralph R. Steinman
Fourth Advisor
Richard C. Oliver
Fifth Advisor
Alvin V. Schiess
Degree Name
Master of Science (MS)
Degree Level
M.S.
Year Degree Awarded
1967
Date (Title Page)
6-1967
Language
English
Library of Congress/MESH Subject Headings
Glucose; Phagocytosis
Type
Thesis
Page Count
vi; 50
Digital Format
Digital Publisher
Loma Linda University Libraries
Copyright
Author
Usage Rights
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Recommended Citation
Adams, Donald F., "The Effect of Glucose on Neutrophilic Phagocytosis" (1967). Loma Linda University Electronic Theses, Dissertations & Projects. 1415.
https://scholarsrepository.llu.edu/etd/1415
Collection
Loma Linda University Electronic Theses and Dissertations
Collection Website
http://scholarsrepository.llu.edu/etd/
Repository
Loma Linda University. Del E. Webb Memorial Library. University Archives