Abstract

Alzheimer’s disease effects millions of people, yet pharmacological treatments are limited. In the absence of effective treatments, identifying factors that can decrease the risk of developing Alzheimer’s disease is of significant interest. A growing body of epidemiological and experimental evidence suggests that dietary fruits and vegetables can have neuroprotective effects against the harmful effects of oxidative stress, neuroinflammation, and aging. These effects are mediated by various phytochemicals, which are compounds found in plants that can possess antioxidant, anti-inflammatory, and other beneficial properties. This review addresses epidemiological and experimental evidence for the effects and potential mechanisms of several commonly consumed phytochemicals on Alzheimer’s disease neuropathology and outcomes. The data suggest that regular consumption of bioactive phytochemicals from a variety of fruits and vegetables attenuates age- and insult-related Alzheimer’s disease neuropathology.

LLU Discipline

Psychology

Department

Psychology

School

School of Behavioral Health

First Advisor

Richard E. Hartman

Second Advisor

Grace J. Lee

Degree Name

Doctor of Psychology (PsyD)

Degree Level

Psych.D.

Year Degree Awarded

2021

Date (Title Page)

9-2021

Language

English

Subject - Local

Alzheimer Disease--drug therapy; Phytochemicals--Therapeutic use.

Type

Doctoral Project

Page Count

81 p.

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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Psychology Commons

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