Twenty-five pregnant women were recruited for this study as they presented for elective cesarean section at term. Comparison was made between 10 diabetic women and 15 nondiabetic women: 13 nondiabetic women with normal weight babies and six diabetic women with macrosomic babies. Radial artery, uterine vein, umbilical vein, and umbilical artery blood samples were analyzed in the fasting state for lipoprotein composition. Diabetic and diabetic-macrosomic infants had greater birth weight and skinfold measurements but not greater birth length.
It appears that higher triglyceride (TG) levels found A in diabetics (p=0.035) are transferred to the fetus more efficiently (p=0.009) than in nondiabetics. Triglyceride levels however, did not correlate with skinfold measurements. Strong negative correlation was found between skinfolds and both radial artery total cholesterol (r=-0.78; p=0.001) and HDL-C (r=-0.76; p=0.001).
KEYWORDS: diabetic pregnancy, macrosomia, umbilical plasma lipids, maternal plasma lipids.
Patricia K. Johnson
James W. Blankenship
Elmer P. Sakala
Gerald W. Shavlik
Master of Science (MS)
Year Degree Awarded
Date (Title Page)
Library of Congress/MESH Subject Headings
Pregnancy in Diabetics; Fetal Macrosomia; Lipids
Loma Linda University Libraries
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Butler, Dianne Greive, "Maternal and Umbilical Plasma Lipids Obtained During Elective Cesarean Section as Predictors of Macrosomia in Diabetic Pregnancy" (1987). Loma Linda University Electronic Theses, Dissertations & Projects. 1206.
Loma Linda University Electronic Theses and Dissertations
Loma Linda University. Del E. Webb Memorial Library. University Archives