Antibacterial Effects of Various Endodontic Irrigants and Medicaments on Selected Anaerobic Bacteria
Abstract
This study was undertaken to determine the antibacterial effects of various endodontic irrigants and medicaments against six selected anaerobic bacteria. In part 1, the organisms were mixed separately with dilutions of six irrigants in tubes containing fluid thioglycolate broth and allowed to remain in contact for specific time periods before being evaluated for growth. In part 2, the vapors of six medicaments were tested using agar plates streaked with the bacteria.
For part 1, the six irrigants were ranked as to their ability to inhibit bacterial growth. Statistical analysis showed that chlorhexidine and hydrogen peroxide were significantly more effective as antibacterial agents than calcium hydroxide and saline.
For part 2, a zone of inhibition was recorded for each plate and the results analyzed statistically. Formocresol produced significantly larger zones of inhibition than any of the other medicaments.
The results of this study indicated that chlorhexidine and formocresol were the most effective antibacterial agents under the test conditions.
Department
Dentistry
School
School of Dentistry
First Advisor
Mahmoud Torabinejad
Second Advisor
James D. Kettering
Third Advisor
Donald L. Peters
Degree Name
Master of Science (MS)
Degree Level
M.S.
Year Degree Awarded
1992
Date (Title Page)
8-1992
Language
English
Library of Congress/MESH Subject Headings
Bacteria, Anaerobic -- drug effects; Chlorhexidine -- therapeutic use; Dental Pulp Diseases -- therapy; Formocresols -- therapeutic use; Root Canal Irrigants -- analysis
Type
Thesis
Page Count
1 v; 46
Digital Format
Digital Publisher
Loma Linda University Libraries
Copyright
Author
Usage Rights
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Recommended Citation
Ohara, Patrick K., "Antibacterial Effects of Various Endodontic Irrigants and Medicaments on Selected Anaerobic Bacteria" (1992). Loma Linda University Electronic Theses, Dissertations & Projects. 1593.
https://scholarsrepository.llu.edu/etd/1593
Collection
Loma Linda University Electronic Theses and Dissertations
Collection Website
http://scholarsrepository.llu.edu/etd/
Repository
Loma Linda University. Del E. Webb Memorial Library. University Archives