Abstract

This article discusses the current information on the mechanism of the biological signaling that takes place to bring about orthodontic tooth movement.

Currently, there are two general theories as to how orthodontic mechanical force is translated to biologically meaningful signals for the cells of the periodontium. These include a cellular-humoral response and a bioelectric response.

There are various mechanisms utilized by the cells of the periodontium to bring about the cellular-humoral response. These include: The activation of the cells of the immune system to synthesize and release specific chemicals (cytokines) which affect cell function, direct effects of mechanical force on the cells of the periodontium, and changes in the local oxygen availability caused by the application of force.

The bioelectric response involves the generation of two types of electrical signals: A piezoelectric potential generated from the distortion of the hydroxylapatite crystals and a bioelectric potential generated from the metabolically active cells of the alveolar bone.

LLU Discipline

Orthodontics

Department

Dentistry

School

Graduate School

First Advisor

Philip Boyne

Second Advisor

Joseph Caruso

Third Advisor

Michael Fillman

Fourth Advisor

Toufic Jeiroudi

Fifth Advisor

Leroy Leggitt

Sixth Advisor

David Rynearson

Seventh Advisor

Willis Schlenker

Eighth Advisor

James Farrage

Year Degree Awarded

1995

Date (Title Page)

12-1995

Language

English

Library of Congress/MESH Subject Headings

Tooth Movement, Minor; Immune System; Cell Communication; Mast Cells; Monocytes; Cytokines; Cytoskeleton; Prostagladins

Type

Thesis

Page Count

vi; 40

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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