Abstract

Inflammation of the connective tissue adjacent to the periodontal pocket may depend on the continuous presence of bacteria. Following periodontal treatment, subgingival plaque accumulation may interfere with healing. The purpose of this study was to determine the effect of irrigation with chlorhexidine or oxytetracycline on the cultivable bacteria in standardized chronic periodontal pockets in dogs. Chronic periodontal pockets were irrigated with either 5 ml. of 2 percent chlorhexidine or 250 mg. of oxytetracycline in 5 ml. distilled water. The pockets were irrigated dally for two days and were sampled on the first, fourth, seventh, fourteeth, twenty-first, thirty-fifth and forty-second days following the last irrigation. The samples were removed by means of a sterile barbed broach wrapped with calcium alginate fibers as described by Crawford et al. (lADR Abstr. #288, 1973). The samples were protected during the procedure by gassing with 02-free gas. Anaerobic dispersal, dilution, and plating were performed as previously described (Manganiello, et al. lADR Abstr. #501, 1971). Cultivable bacteria were counted on blood agar plates incubated in air, in Brewer jars or on roll tubes. Results indicate that oxytetracycline irrigation reduced up to 100 percent the number of cultivable bacteria sampled at day one. Irrigation with chlorhexidine eliminated up to 99 percent of the bacteria as compared with control defects.

LLU Discipline

Periodontics

Department

Periodontics

School

Graduate School

First Advisor

W. Eugene Rathbun

Second Advisor

Richard C. Oliver

Third Advisor

Max Crigger

Fourth Advisor

Robert Kiger

Fifth Advisor

Grenith J. Zimmerman

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1975

Date (Title Page)

5-1975

Language

English

Library of Congress/MESH Subject Headings

Gingival Diseases -- therapy; Oxytetracycline; Chlorhexidine

Type

Thesis

Page Count

vi; 26

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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