Abstract

This paper describes 39 cases of oral verrucous carcinoma. This study reports on 20 cases from the San Diego Tumor Group and 19 cases from the Oral Pathology Service which showed the characteristic features of verrucous carcinoma. Twenty three patients were men and 16 were women. In the majority of the cases the lesion was exophytic and had a papillary surface. The buccal mucosa and gingiva were the sites most frequently involved. The characteristic histologic pattern consisted of keratinized well-differentiated epithelium exhibiting irregular folds. In addition there was an inward projection of bulbous rete ridges. Surgical excision was the treatment of choice in all but one case. There were 10 reported recurrences among the 25 cases in which follow-up information was available. Three of these cases had multiple recurrences. In one patient there was a lymph node metastasis originating from a primary verrucous carcinoma, A recurrence diagnosed as invasive squamous cell carcinoma occurred in the one patient initially treated with Cobalt 60. Only 15% of the patients reported being tobacco chewers.

Department

Dentistry

School

Graduate School

First Advisor

Francis V. Howell

Second Advisor

Elmer E. Kelln

Third Advisor

Gordon M. Rick

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1974

Date (Title Page)

6-1974

Language

English

Library of Congress/MESH Subject Headings

Odontogenic Tumors; Mouth Neoplasms

Type

Thesis

Page Count

v; 24

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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