The Effect of an Anti-Osteoclastic Agent and a Collagen Sponge on Root Resorption Following Regenerative Periodontal Surgery in the Dog

Author

Rudolf Hahn

Abstract

Previous studies indicate that root resorption is a frequent sequela to significant amounts of periodontal repair following experimental regenerative periodontal surgical procedures in animal models. To study if root resorption can be reduced or prevented, periodontal repair was evaluated in large horizontal circumferential defects in the dog in the absence of influence from the oral environment. Diphosphonate (Cl₂ MDP) applied topically to the root surfaces prior to wound closure as well as the use of a collagen sponge membrane (Helistat®) draped over the root surfaces and a control with no additional treatment after defect creation were the modalities employed. Wound closure involved the total submergence of the teeth. Following a four month healing period periodontal repair was analyzed histologically. The results showed very similar healing in all three treatment modalities. Extensive root resorption had accompanied regeneration. This study found that the use of an anti-osteoclastic agent (Diphosphonate), nor the use of a collagen sponge draped over the surgically denuded root surfaces influenced the resorptive activity.

LLU Discipline

Periodontics

Department

Periodontics

School

Graduate School

First Advisor

Rolf Nilveus

Second Advisor

Noel Claffey

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1989

Date (Title Page)

8-1989

Language

English

Library of Congress/MESH Subject Headings

Root Resorption -- prevention & control; Membranes, Artificial; Bone Regeneration; Wound Healing; Diphosphonates; Collagen

Type

Thesis

Page Count

2 ii; 42

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Copyright

Author

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Recommended Citation

Hahn, Rudolf, "The Effect of an Anti-Osteoclastic Agent and a Collagen Sponge on Root Resorption Following Regenerative Periodontal Surgery in the Dog" (1989). Loma Linda University Electronic Theses, Dissertations & Projects. 2249.
https://scholarsrepository.llu.edu/etd/2249

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives