Abstract

The present study is a histological evaluation of condyles taken from rabbits that underwent either a midline or paramedian distraction osteogenesis procedure on the mandibles. Fifteen rabbits were originally operated on and eight of these fifteen successfully made it through both the distraction osteogenesis procedure and the 1 month holding period that followed. There was one control animal.

In the present study, the condyles from these nine rabbits (1 control, 2 midline distraction osteogenesis, 6 paramedian distraction osteogenesis) were prepared for histological evaluation (18 total). Step serial sections were cut along the coronal plane and the sections from the anterior halves of the condyles were furthered evaluated.

The bone density of areas immediately adjacent to the cartilaginous surface on these condyles was measured in triplicate using a point counting method. Two areas were studied: the first was the area of bone 1 mm below the cartilage and the second was the area of bone 0.5 mm below the cartilage. The bone density measurements within the 0.5 mm areas were further divided between medial and lateral halves.

The area of the cartilage on the surface of each condyle was calculated. The articular layer of the cartilage was determined for each condyle and the area of this layer was also calculated. These areas were also divided into medial and lateral halves.

Results showed one out of four comparisons of bone density at the 1 mm level and two out of eight comparisons at the 0.5 mm level with a statistically significant difference. One out of sixteen comparisons of cartilage areas showed a statistically significant difference. There were no clinically significant differences in bone density between the left and right condyles of each treated group. The results also showed that there were no clinically significant differences in condyles from animals that underwent midline distraction osteogenesis and those from animals that underwent paramedian distraction osteogenesis. The same results were true for the calculations of cartilage areas, both total and articular.

LLU Discipline

Orthodontics and Dentofacial Orthopedics

Department

Orthodontics and Dentofacial Orthopedics

School

Graduate School

First Advisor

Joseph M. Caruso

Second Advisor

Philip Boyne

Third Advisor

Alan Herford

Fourth Advisor

Jay Kim

Fifth Advisor

Leroy Leggitt

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

2003

Date (Title Page)

12-2003

Language

English

Library of Congress/MESH Subject Headings

Osteogenesis, Distraction; Facial Bones; Bone Density; Temporomandibular Joint

Type

Thesis

Page Count

ix; 2003

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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