Abstract
An in vitro study using radioactively-labeled tissue culture cells was conducted over a seven-month period on Grossman's sealer, Rickert's sealer, N2 Permanent, and Cavit to determine the lasting and relative tissue toxicity of these materials.
From this study it was observed that all materials possess lasting tissue toxicity. When relative toxicity is considered, Grossman's is the most toxic, followed by N2, Rickert's and Cavit in descending order of toxicity. Both Grossman's and N2 would be considered highly toxic, with Rickert's displaying moderate toxicity. Cavit would be considered mild to moderate in toxicity.
The use of radioactively-labeled tissue cells as a method of testing root canal filling materials is a rapid, highly sensitive method which allows adequate cell-material contact and permits objective quantitation of cell damage with accuracy.
School
Graduate School
First Advisor
William L. Young
Second Advisor
Ronald E. Buell
Third Advisor
Raleigh R. Cummings
Fourth Advisor
R. G. Hall, Jr.
Degree Name
Master of Science (MS)
Degree Level
M.S.
Year Degree Awarded
1975
Date (Title Page)
5-1975
Language
English
Library of Congress/MESH Subject Headings
Dental Amalgam; Root Canal Filling Materials
Type
Thesis
Page Count
77 pg.
Digital Format
Digital Publisher
Loma Linda University Libraries
Copyright
Author
Usage Rights
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Recommended Citation
Antrim, Donald D., "An Evaluation of the Cytotoxicity of Root Canal Filling Materials on Tissue Culture Cells In Vitro: Grossman's Sealer, N2 Permanent, Rickert's Sealer, and Cavit" (1975). Loma Linda University Electronic Theses, Dissertations & Projects. 2445.
https://scholarsrepository.llu.edu/etd/2445
Collection
Loma Linda University Electronic Theses and Dissertations
Collection Website
http://scholarsrepository.llu.edu/etd/
Repository
Loma Linda University. Del E. Webb Memorial Library. University Archives
Included in
Dental Materials Commons, Endodontics and Endodontology Commons, Medical Toxicology Commons