Abstract

Endodontic therapy was evaluated as a possible control or prevention modality of radiation type dental caries in dogs. Two adult male dogs with permanent dentitions had endodontic therapy performed on alternating teeth in each jaw. The nontreated teeth served as controls.

The dogs were irradiated with 7000 rad Cobalt-60 radiation fractionated over an eight week period. The dogs were killed at 60 and 182 days post-irradiation. The teeth were removed from the jaws and immersed in methylene blue dye, sectioned, and the dye penetration pattern photographed. Diffusion of the dye into the tooth structure was quantified and statistically analyzed.

A marked difference was seen between the treated and untreated teeth from the 60 day animal. The endodontically treated teeth showed significantly less dye penetration than did the untreated teeth (P < 0.005). There were no significant differences between the treated and untreated teeth from the 182 day animal (P > 0.05). Analysis of covariance showed no significant differences between the groups.

The findings are discussed and suggestions are made for further study and corrections in the experimental model.

It was concluded that endodontically treated teeth showed significantly less demineralization in short term observations and that the dog may or may not be determined a good model for studying caries based on this data.

Department

Dentistry

School

Graduate School

First Advisor

Donald L. Brewer

Second Advisor

Raleigh R. Cummings

Third Advisor

Ralph R. Steinman

Fourth Advisor

William L. Young

Fifth Advisor

Grenith J. Zimmerman

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1977

Date (Title Page)

6-1977

Language

English

Library of Congress/MESH Subject Headings

Endodontics; Dogs

Type

Thesis

Page Count

viii; 31

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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