Abstract
Craig and Harrison12 examined the effect of demineralization of resected root ends on wound healing following periradicular surgery. Based on its microscopic evaluations from 4-45 days, it was proposed that demineralization of resected root ends enhances cementogenesis. The purpose of this study was to investigate the longer term effects of demineralization on cementogenesis using Mineral Trioxide Aggregate (MTA) or amalgam as root end filling materials. After completion of root canal therapy and endodontic surgery on seventy-two roots of mandibular second, third and fourth premolars of six beagle dogs, 32/72 of the root ends at random were etched with 50% citric acid (pH 1.0) for two minutes and the other 40/72 received no etching treatment. The root end cavities were then filled with either MTA or amalgam. The animals were sacrificed either 2 or 4 months later. Block sections containing the teeth and their surrounding tissues were removed, fixed, decalcified, sectioned, stained with H&E, and examined histomorphometrically in a double blind manner. The resected root ends were examined for cementum formation and degree of inflammation. The results were statistically analyzed using an independent t test with unequal variance. The results showed cementogenesis over resected root ends in both amalgam and MTA samples. In contract to amalgam, the use of MTA in the non-etched samples resulted in formation of cementum over this material. No significant difference was found between the amount of cementum formation on the resected root ends with and without acid etching for both amalgam and MTA. It was concluded that cementogenesis occurs in resected root ends eventually with or without acid etching but this procedure inhibits cementogenesis over the MTA.
Department
Dentistry
School
Graduate School
First Advisor
Mahmound Torabinejad
Second Advisor
Douglas J. McKendry
Third Advisor
Paul McMillan
Degree Name
Master of Science (MS)
Degree Level
M.S.
Year Degree Awarded
1997
Date (Title Page)
12-1997
Language
English
Library of Congress/MESH Subject Headings
Tooth Demineralization; Dental Cementum; Root Canal Filling Materials; Root Canal Therapy
Type
Thesis
Page Count
vii; 63
Digital Format
Digital Publisher
Loma Linda University Libraries
Copyright
Author
Usage Rights
This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Recommended Citation
Abedi, Hamid R., "The Effect of Root End Demineralization On Cementogenesis : A Long Term Investigation" (1997). Loma Linda University Electronic Theses, Dissertations & Projects. 2468.
https://scholarsrepository.llu.edu/etd/2468
Collection
Loma Linda University Electronic Theses and Dissertations
Collection Website
http://scholarsrepository.llu.edu/etd/
Repository
Loma Linda University. Del E. Webb Memorial Library. University Archives
Included in
Animal Experimentation and Research Commons, Dental Materials Commons, Endodontics and Endodontology Commons, Laboratory and Basic Science Research Commons