Shuliang Lee

Abstract

The work on the active substance of Eremocarpus setigerus Benth has been previously performed by Naito and Noller. However, the investigation was not complete. Therefore we isolated and tested this substance by steam distillation and thin layer chromatography technique. A yellow sticky toxic substance was isolated with Rf values of 0.15 in benzene system and 0.57 in benzene-absolute ethanol (95:5 v/v) system.

The toxic substance which is free of halogen, nitrogen, and sulfur, is soluble in ethyl ether, ethanol, and concentrated sulfuric acid. It has a maximum absorption in the ultraviolet region that indicates the presence of unsaturation. Its infrared spectrum indicates the presence of a·saturated tertiary or a highly symmetrical secondary hydroxyl group and carbonyl group. The functional group tests also indicate the presence of ketone, ester, enol and isolated double bond groups. We believe that the enol form is attributed to the conjugation of the ketone and the ester groups at a β-carbon position.

Furthermore, the toxic substance gave a positive terpene-terpenoid test. This leads us to believe that the toxic substance might belong to the triterpenoid series.

Department

Chemistry

School

Graduate School

First Advisor

Laurence W. Botimer

Second Advisor

Earl W. Lathrop

Third Advisor

William D. Leech

Fourth Advisor

Maurice E. Mathisen

Fifth Advisor

Wayne E. Zaugg

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1968

Date (Title Page)

5-1968

Language

English

Library of Congress/MESH Subject Headings

Poisonous plants; Chromatographic analysis

Type

Thesis

Page Count

v; 26

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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