Use of Dyes with Rapid Bloodstream Clearance for Serial Determination of Cardiac Output

Document Type

Article

Publication Date

1-1-1958

Publication Title

Proceedings of the Society for Experimental Biology and Medicine

ISSN

00379727

E-ISSN

15353699

Abstract

Bloodstream clearance rates and spectral absorption curves of 38 blue dyes have been investigated. The results suggest that suitable dyes for frequent serial estimation of the cardiac output are Patent Blue A, Brilliant Blue, and Patent Blue V. These dyes leave the bloodstream rapidly after injection; they have an adequate build-up of concentration during the first minute: and their maximum spectral absorption occurs at wave lengths of 630 mμ or higher. Cardiac output values obtained in dogs with Patent Blue A, Brilliant Blue, Patent Blue V, and T-1824 dyes are presented and compared. © 1958, SAGE Publications. All rights reserved.

Volume

98

Issue

2

First Page

345

Last Page

347

DOI

10.3181/00379727-98-24038

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