Results of treatment of coronary arteriosclerosis with choline

Document Type

Article

Publication Date

1-1-1950

Publication Title

American Heart Journal

ISSN

00028703

E-ISSN

10976744

Abstract

1. 1. A series of 115 patients with proved coronary thrombosis and myocardial infarction were treated with choline for periods of one to three years after recovery from the immediate attack. These patients were compared to 115 control patients who were alternately admitted to the hospital with the same diagnosis but who did not receive choline treatment. 2. 2. The dosage of oral choline averaged 12 grams daily. It was taken for one year by 52 subjects, for two years by 35 subjects and for three years by 28 subjects. 3. 3. The subsequent mortality rate of patients who had suffered an acute coronary thrombosis with myocardial infarction appeared to be significantly reduced by the treatment with choline in this series of patients. 4. 4. These studies suggest that the lipotropic agent choline is of value in the treatment of coronary arteriosclerosis and would appear to merit further trial and observation in this disease. © 1950.

Volume

39

Issue

5

First Page

729

Last Page

736

DOI

10.1016/0002-8703(50)90132-3

PubMed ID

15413581

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