Title
Novel Technologies in Studying Brain Immune Response
Document Type
Article
Publication Date
1-1-2021
Publication Title
Oxidative Medicine and Cellular Longevity
ISSN
19420900
E-ISSN
19420994
Abstract
Over the past few decades, the immune system, including both the adaptive and innate immune systems, proved to be essential and critical to brain damage and recovery in the pathogenesis of several diseases, opening a new avenue for developing new immunomodulatory therapies and novel treatments for many neurological diseases. However, due to the specificity and structural complexity of thecentral nervous system (CNS), and the limit of the related technologies, the biology of the immune response in the brain is still poorly understood. Here, we discuss the application of novel technologies in studying the brain immune response, including single-cell RNA analysis, cytometry by time-of-flight, and whole-genome transcriptomic and proteomic analysis. We believe that advancements in technology related to immune research will provide an optimistic future for brain repair.
Volume
2021
DOI
10.1155/2021/6694566
PubMed ID
33791073
Recommended Citation
Li, Li; Lenahan, Cameron; Liao, Zhihui; Ke, Jingdong; Li, Xiuliang; Xue, Fushan; and Zhang, John H., "Novel Technologies in Studying Brain Immune Response" (2021). LLU Faculty Publications. 287.
https://scholarsrepository.llu.edu/fac_pubs/287