The nature of the hemagglutinating agent noted in the blood serum of patients with viral hepatitis

Document Type

Article

Publication Date

7-1-1961

Publication Title

The Journal of Laboratory and Clinical Medicine

ISSN

00222143

Abstract

Animals were immunized against rhesus erythrocytes agglutinated with serum of patients with infectious hepatitis, and against sheep erythrocytes agglutinated by infectious mononucleosis sera. The resulting antisera were found to contain antiglobulin antibodies as shown by their ability to agglutinate human group O Rh-positive red cells sensitized by anti-Rh incomplete antibody. The presence of antiglobulin antibody in the immune rabbit sera indicates that the agglutinating agents in infectious hepatitis and infectious mononucleosis are globulin in nature, and the agglutination is considered to be due to antibody action rather than to the presence of a hemagglutinating virus. © 1961.

Volume

58

Issue

1

First Page

104

Last Page

106

PubMed ID

13716303

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