Abstract

The periapical dental granuloma and cyst is the most frequent sequela of pulpitis. These lesions are always intraosseous and often become quiescent after the acute phases are over, forming a space which primarily consists of chronic inflammatory tissue. This chronic inflammatory tissue usually appears as a one-centimeter area of punched out bone on the x-ray film and is referred to as a dental granuloma. Should epithelium choose to proliferate in this inflammatory area, it may undergo subsequent cystic degeneration forming the typical periapical cyst. While much has been written with regard to the etiology and treatment of the apical cyst and granuloma, descriptions of microscopic findings appear to be the result of small sample-size studies and/or the experience of various dental pathologists.

In this study, a series of 200 apical lesions were analyzed microscopically; 100 of these were granulomas and 100 were periapical cysts. With this rather large sample size, references were made to tooth location, age incidence, and the various histologic findings. While the basic concept of the histopathology of the periapical cyst and granuloma has not been altered, this paper presents findings and incidence of various atypical infiltrations and variations such as eosinophils, macrophages, multiple giant cells, Russell bodies and atypical epithelium.

Department

Dentistry

School

Graduate School

First Advisor

Ronald E. Buell

Second Advisor

Edwin M. Collins

Third Advisor

Elmer E. Kelln

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1971

Date (Title Page)

5-1971

Language

English

Library of Congress/MESH Subject Headings

Periapical Granuloma; Radicular Cyst

Type

Thesis

Page Count

v; 35

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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