John Rozema

Abstract

This experiment was designed to evaluate an oral surgical dressing which may be used as an aid to healing tissue. The parameters of evaluation were directed toward wound healing enhancement, duration, and stability of the bandage. A histological evaluation of the surgical wounds protected with the bandage as compared to the control wounds was made.

The surgeries were performed on eight dogs in a double controlled experiment and were in the form of bilateral maxillary gingivectomies and mandibular molar tooth extractions. The surgery sites on the left were covered with the Orahesive Bandage while the right side remained exposed to the environment of the oral cavity. The surgeries were performed under pentobarbital sodium using a drape and a clean to sterile oral surgical technique. The animals were then killed at various intervals and the maxilla and mandible removed and placed in 10% formalin solution. The specimens were then decalcified, processed and slide preparations made for microscopic observation. Evaluation of the specimens were performed in three stages: (1) the clinical; (2) the gross sectioning; (3) the microscopic interpretation.

In general terms, the protection of the gingival and the extraction wounds by the oral bandage enhanced the early healing process and allowed epithelialization to occur more rapidly than in similar surgical wounds which were not protected. The most distinguishing features were the lack of neutrophils and the absence of wound protuberance in the gingival surgical specimens from the bandaged side. In none of the sections was there any evidence of rejection of the bandage material, and there was no foreign body reaction which could be attributable to the material used in the experiment.

School

Graduate School

First Advisor

Bernard Clinton Byrd

Second Advisor

Elmer Ellsworth Kelln

Third Advisor

Irving Rappaport

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1968

Date (Title Page)

6-1968

Language

English

Library of Congress/MESH Subject Headings

Occlusive Dressings

Type

Thesis

Page Count

iv; 31

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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