Abstract

The objectives of this study were to develop an animal model for testing oral bone and marrow transplantation that is adaptable to immunological studies; to determine the effect of an isogeneic graft of cancellous bone and marrow on the healing of surgically created defects; and to determine the fate of grafted isogeneic cancellous bone and marrow transplanted into defects. Fourteen CBA/H mice served as experimental animals and bilateral intraoral defects were prepared. The experimental side received isogeneic graft material while the other side served as a control. Osseous healing was found to be accelerated in the defects receiving graft material as compared to the controls. The graft material appeared to grow within the defect and then fuse with the healing callus.

LLU Discipline

Periodontics

Department

Periodontics

School

Graduate School

First Advisor

W. Eugene Rathbun

Second Advisor

Richard C. Oliver

Third Advisor

R. Leslie Arnett

Fourth Advisor

Jan Egelberg

Degree Name

Master of Science (MS)

Degree Level

M.S.

Year Degree Awarded

1972

Date (Title Page)

6-1972

Language

English

Library of Congress/MESH Subject Headings

Graft Survival; Bone Marrow

Type

Thesis

Page Count

v; 18

Digital Format

PDF

Digital Publisher

Loma Linda University Libraries

Usage Rights

This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Collection

Loma Linda University Electronic Theses and Dissertations

Collection Website

http://scholarsrepository.llu.edu/etd/

Repository

Loma Linda University. Del E. Webb Memorial Library. University Archives

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