The Dr. George M. Austin Neurology Research Collection
Document Type
Conference Proceeding
Publication Date
2-1993
Abstract
''lntracranial Aneurysm: A model of expansion to critical thinning," Poster Presentation Annual Meeting of Biophysical Society, Wash., D.C., 1993, 9 p.
Most intracranial aneurysms (IA) are thinner at the apex; and 84% rupture at the apex. (Weir, 1987, Crompton, 1966). Minimum thickness of an unruptured aneurysm is reported 20 microns (Suzuki, et al 1980). We have developed a computer model of aneurysm enlargement starting from a vascular wall using the membrane elasticity equations of Green and Adkins, 1960 and Bogen & McMahon, 1978, and a computer solution with a new Fortran program by X. Gong. The relatively homogeneous wall (Austin, et al 1973) enlarges with suprathreshold pressure increments and is assumed incompressible. Parameters include initial neck diameter, initial wall thickness, material constant, relative Young's Modulus, relative initial apex inflation, and curvature at the apex. The enlarging aneurysm is non-spherical with cylindrical symmetry. Growth of the aneurysm shows increased thinning toward the apex and a predictable minimum volume for the threshold thickness at rupture. Graphic results are displayed to show pressure-volume, thickness-apex distance, and thickness-pressure relations. The graphic and pictorial plot of aneurysm volume versus wall thickness and diameter, predicts proximity to rupture for given initial parameters.
Recommended Citation
Austin, G.; Gong, X.; and Suo, Z., "Descriptive Enlargement of Intracranial Aneurysms to a Critical Thickness for Rupture" (1993). The Dr. George M. Austin Neurology Research Collection. 32.
https://scholarsrepository.llu.edu/george-austin-collection/32